glp-1 receptors Glucagon-like peptide-1 receptor: mechanisms and advances in therapy GLP-1R Signaling and Functional Molecules
Description
The SELECT cardiovascular outcomes trial showed that semaglutide 2.4 mg significantly reduced major adverse cardiovascular events (heart attack, stroke, and cardiovascular death) in patients with established cardiovascular disease and overweight or obesity, even without type 2 diabetes

doi: 10.1038/ijo.2013.149 91 le RouxCWAstrupAFujiokaKGreenwayFLauDCWVan GaalLet al

Why do clinical trial results differ from real-world outcomes

T2D, type 2 diabetes mellitus

Experts say that patients and clinicians must be aware of severe side effects like gastroparesis and its consequences
