how were glp 1 agonists discovered History of GLP-1 Medications Reflections on the discovery GLP-1
Description
Nausea comes primarily from the GLP-1 component, which slows gastric emptying (how quickly food leaves your stomach)

female average starting intake: 16 2 g)

GLP-1R, a core member of the GPCR family, is widely present on the surfaces of various cells in the human body

Cotadutide is safe with the most common side effects being mild to moderate nausea and vomiting, but with no greater severity or frequency than found in GLP-1 agonists [44]

There are so many mysterious parts here that we don't know. The completed clinical trials for GLP-1 drugs only focused on patients with type 2 diabetes or obesity