glp-1 insulin secretion Schematic pathway showing release of by GLP-1. Binding of The Physiology of Glucagon-like Peptide

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Yes, especially during the first 4 to 8 weeks when calorie intake drops significantly and the body has not yet adapted to lower energy availability

The metabolic benefits were there: steady weight loss and declining inflammation markers

7-9 GLP-1 signaling has been shown to promote microglia-mediated expression of neurotrophic factors, such as brain-derived neurotrophic factor and nerve growth factor, to promote neuronal survival and inhibit stress pathways in neurodegenerative conditions

Endocrinology (1999) 140:228