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38 , 39 , 40 , 41 , 42 , 43 The STEP 6 trial population comprised mainly Japanese participants (90%) with the remainder from South Korea

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Posttranslational processing of preproglucagon The vast majority of glucagon is produced in the pancreatic -cells, but, under some conditions, small amounts of glucagon also have been detected in the intestinal L-cells [87], although the validity of immunoassays to distinguish different proglucagon products has been questioned, and some reports were unable to find genuine glucagon in the intestine by mass spectrometric analysis [[144], [145], [146]]

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