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Many users find that the gastrointestinal side effects serve as a behavioural deterrent to consuming high-fat foods, which can reinforce dietary compliance

A 2023 UK trial published in eClinicalMedicine demonstrated that monthly Sublocade was superior to daily standard of care (methadone or sublingual buprenorphine) for maintaining abstinence from non-medical opioid use over 24 weeks

Wegovy should be used in addition to a reduced-calorie diet and increased physical activity
