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[DOI] [PMC free article] [PubMed] [Google Scholar] 267.Wing R.R., Papandonatos G., Fava J.L., Gorin A.A., Phelan S., McCaffery J., Tate D.F

By acting like this hormone, semaglutide affects several parts of the body, including the brain, stomach, and pancreas

These studies suggest it may help your body use insulin more efficiently, which can help decrease the risk of weight gain

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However, the clinical data suggests that the combined effect of all three receptor targets results in improved overall glycaemic control, with the GLP-1 and GIP effects appearing to counterbalance any blood sugar raising tendency from the glucagon component