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glp-1/glucagon dual receptor agonist PDB-101: Molecule of the Month: GLP-1 Agonists Polyagonists Enable Increasingly Effective Treatment

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Peer review Peer review information Nature Medicine thanks Kevin Wing and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

glp-1/glucagon dual receptor agonist PDB-101: Molecule of the Month: GLP-1 Agonists Polyagonists Enable Increasingly Effective Treatment

doi:10.1016/j.bbrc.2017.06.031 41

glp-1/glucagon dual receptor agonist PDB-101: Molecule of the Month: GLP-1 Agonists Polyagonists Enable Increasingly Effective Treatment

A study reported that GLP-1(7-36) could protect HT22 cells against stressors via activation of survival signaling molecules, such as Akt and ERK1/2 (183)

glp-1/glucagon dual receptor agonist PDB-101: Molecule of the Month: GLP-1 Agonists Polyagonists Enable Increasingly Effective Treatment

What Is GLP1 and Why Does It Matter

glp-1/glucagon dual receptor agonist PDB-101: Molecule of the Month: GLP-1 Agonists Polyagonists Enable Increasingly Effective Treatment

47 However, it is not advised during pregnancy as it is considered a class C drug, defined as a drug with established risk that cannot be ruled out

glp-1/glucagon dual receptor agonist PDB-101: Molecule of the Month: GLP-1 Agonists Polyagonists Enable Increasingly Effective Treatment

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