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If b12 was added specifically for theoretical semaglutide effects and your levels test normal, stopping supplementation makes sense
The FDA does note that during a drug shortage, compounded versions can be produced if they meet Federal Food, Drug and Cosmetic Act requirements, but urged caution
Additionally, prescription weight loss drugs are often expensive without substantial insurance coverage
Bu H, Li L, Li X, Guo J
Recent research has discovered that metformin can inhibit FXR signaling by altering gut bacteria, leading to increased GLP-1 production and release in a way that does not depend on AMPK activation (Sun et al., 2018)
