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Both medications cause nausea and stomach upset in some patients, especially early in treatment during dose escalation

Semaglutide withdrawal symptoms when stopping the medication are similar to those experienced with tirzepatide, including appetite return and potential weight regain if proper strategies are not implemented

The researchers could not conclusively prove that semaglutide directly causes NAION, and noted that other factors (such as underlying cardiovascular conditions common in diabetic patients) may play a role

Our deeper breakdown of retatrutide trial results covers the dose-by-dose data in more detail

Validated screening tools that can help to flag psychological problems that may require follow-up or referral to a mental health specialist have been developed for most problem areas and are available in multiple languages