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Glucose and insulin tolerance tests In order to assess the effects of the different pharmacotherapies on glucose tolerance, animals were subjected to an intraperitoneal glucose tolerance test (GTT) during the third week of treatment, 24 h after the last drug administration

12.2 Pharmacodynamics Onset of Action The pharmacodynamic profiles for TOUJEO given subcutaneously as a single dose of 0.4, 0.6, or 0.9 U/kg in a euglycemic clamp study in patients with type 1 diabetes showed that on average, the onset of action develops over 6 hours post dose for all three single doses of TOUJEO

References Becton, Dickinson and Company

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