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Deficiencies in vitamin B12 (particularly in patients also taking metformin), iron, and other nutrients have been linked to cognitive symptoms

doi:10.1136/bmj.g2366

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While those with obesity stand to reap considerable health benefits from fat loss, the potential benefits of fat loss among healthy-weight individuals are minimal and are unlikely to offset the sizable health risks associated with reduced lean mass

Use of antithymocyte globulin, belatacept, and minimization or elimination of tacrolimus in the immunosuppressive regimen has been shown to reduce hyperglycemia and new onset PTDM