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They could have, not only effects on some of the manifestations of bipolarity, but also effects on the underlying pathophysiology. Proponents say this could unlock a whole new way to treat bipolar disorder

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Studies like these are hypothesis-generating and serve as a nidus for larger randomized trials to take place, he said

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Semaglutide (GLP-1) targets appetite control and metabolic benefits, while Tirzepatide offers enhanced results through its dual GLP-1 + GIP action

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After pushback from the compounding pharmacies, the agency agreed to reevaluate its decision, but in December 2024, it announced it would be sticking with its original call

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