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A comprehensive bibliometric analysis underscores emerging research directions in GLP-1RAs, such as investigations into novel agents (e.g., tirzepatide, semaglutide) in heart failure with preserved ejection fraction (HFpEF) and renal outcomes [48]

Considering short half-life of native GLP-2 in human circulation and promising results of teduglutide, which half-life is modestly extended to 35 h, current research focuses on an increase of the time of GLP-2 action by developing new, more stable, GLP-2 analogs

doi: 10.1007/s11515-014-1337-8 [DOI] [Google Scholar] 42.Anthony HV, Schapira

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10.1056/nejmoa1603827 51 MiyagawaJ.OdawaraM.TakamuraT.IwamotoN.TakitaY.ImaokaT