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Important to note this was a study in mice, not humans

Common side effects include increased heart rate, elevated blood pressure, dry mouth, insomnia, anxiety, constipation, or mood swings

Because GLP-1 medications improve metabolic health so effectively, they often work too well when paired with old prescriptions, meaning doctors must actively lower or eliminate a patients existing blood pressure pills to avoid over-treatment
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Excessive caffeine can cause anxiety, insomnia, and increased heart rate

Science 364 , 11791184 (2019)
