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Azcoitia et al., 2001
Percentage of subjects with no heavy drinking days: evaluation as an efficacy endpoint for alcohol clinical trials: efficacy endpoint for alcohol trials
[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Mietlicki-Baase E.G., Ortinski P.I., Rupprecht L.E., et al
Longitudinal studies reinforce this perspective, illustrating that poor glycemic control in patients with diabetes can further deteriorate sleep quality, perpetuating a detrimental cycle of worsening health outcomes [53]
The effective semaglutide dose range in this paradigm (0.010.1 mg/kg for males, 0.03-0.1 mg/kg for females) is consistent with doses reported to reduce alcohol self-administration and intake (0.0003-0.01mg/kg) in rodent and nonhuman primate models (0.003-0.01 mg/kg
