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Leaders across healthcare are emphasizing pairing these medications with lifestyle interventions, especially as emerging data points to kidney and cardiovascular benefits

GLP-1 in addiction medicine: GLP-1 acts on pancreas, gut, kidney, heart and thyroid receptors to activate reward/stress hubs (VTA, NAc, ARC, PFC, hypothalamus)

NICE has backed use of the Wegovy (semaglutide) for people with a body mass index (BMI) of 35 kg/m2 or more and at least one weight-related ailment such as high blood pressure, high cholesterol or diabetes as part of a weight management programme involving exercise and a reduce-calorie diet.

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Does Ozempic help with insulin resistance