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Before starting therapy , healthcare providers should conduct a comprehensive assessment including: Cardiovascular history : Document any history of heart disease, arrhythmias, heart failure, or stroke Baseline vital signs : Measure heart rate, blood pressure, and weight Medication review : Identify potential interactions, particularly with antihypertensives, diuretics, and anticoagulants Laboratory tests : Check renal function, liver enzymes, lipid profile, and HbA1c (if diabetic) ECG : Consider baseline electrocardiogram for patients with known cardiac disease or significant risk factors, though this is not routinely required for all patients During treatment , regular follow-up is essential

Kovil highlights another path-breaking finding from that trial

Follow your healthcare provider's instructions and the product information supplied with your medication

When combined, there may be an increased burden of monitoring for adverse effects

The diagnostic gold standard is a secretin stimulation test where secretin is administered and then bicarbonate response is measured in the duodenum