gerd and glp-1 drugs increase risk of acid reflux, GERD, study finds Heartburn on GLP-1s: A Guide
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In fact, some studies found that semaglutide (GLP-1 RA) medications helped people lose an average of 9%-17% of their body weight in a little over a year

The regulatory environment for compounded GLP-1 medications is actively evolving as of May 2026
Heymsfield et al

Others tolerate faster escalation

In adults with type 2 diabetes and heart disease, it is also used to reduce the risk of major cardiovascular events