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doi:10.1200/JCO.2026.44.16_suppl.10548

In a review of clinical trials, the combination of combined oral contraceptive pills (COCPs) with either a GLP-1RA or tirzepatide (GLP-1 and Glucose-dependent insulinotropic polypeptide (GIP) receptors agonist) did not affect the efficacy of contraceptive drugs, even though GLP-1RAs can decrease the absorption of the concomitantly administered drug through their gastric delaying effect

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and global prevalence of type 2 diabetes and obesity, advancements in drug development, and expanding indications for weight loss and cardiovascular health

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