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This is particularly important for medications with a narrow therapeutic index, such as warfarin and digoxin

Drink enough fluids to keep your urine pale yellow, indicating adequate hydration

Estrategias de manejo: Iniciar con dosis bajas y titular gradualmente, tomar la metformina con alimentos, usar formulaciones de liberacin prolongada de metformina, y mantener una hidratacin adecuada pueden minimizar estos sntomas

Furthermore, vacuoles in pancreatic beta cells in young Atg7-KO mice, which suggests cellular degeneration, disappeared in the aged mice in histological analysis

Glucagon is known to influence gut motility, and it is plausible that stimulating these receptors may contribute to altered bowel function
