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In individuals with advanced -cell dysfunction, supplementing insulin therapy with pramlintide, the first and currently only approved injectable short-acting selective analog of amylin, has demonstrated efficacy in enhancing both postprandial and overall glycemic control in both type 2 diabetes (T2D) and type 1 diabetes (T1D) without increasing the risk of hypoglycemia or weight gain

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A two-step MR analysis was further employed to explore potential mediating factors in the T2D-SA relationship

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Explore HbA1c outcomes, safety data, and what the triple agonist's development status means for patients.

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