glp 1 where is it produced GLP-1-based therapies for type 2 diabetes: from single, dual and triple agonists to endogenous GLP-1 production and L-cell differentiation | Diabetology & Metabolic Syndrome Designing GLP-1 delivery: structural perspectives

[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Villanueva-Peacarrillo ML, Martn-Duce A, Ramos-lvarez I, Gutirrez-Rojas I, Moreno P, Nuche-Berenguer B, Acitores A, Sancho V, Valverde I, Gonzlez N

Neuroprotective effects of GLP-1R agonists GLP-1 and its mimetics can cross the BBB, therefore, are able to affect the CNS function such as cognition and neuroprotection (138)

"People with type 2 diabetes are four times as likely to be hospitalized for heart failure, and repeated hospitalizations lead to worse outcomes, making treatment options that improve clinical outcomes crucial," said Mohamed Eid, M.D., M.P.H., M.H.A., vice president, Clinical Development & Medical Affairs, Cardio-Metabolism & Respiratory Medicine, Boehringer Ingelheim Pharmaceuticals, Inc

And this is not a small problem that resolves on its own

We look at whether everything else is optimized, including diet and activity. GLP1 medications can help reduce hunger, but weight loss still depends on how that effect translates into daytoday habits, including what and how much a patient is eating, as well as overall activity levels