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A Joint Advisory on nutritional support for GLP-1 therapy for obesity was issued by the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and the Obesity Society in May of 2025

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Overall, the combined metabolic, neurochemical, and immunomodulatory effects of GLP-1 RAs suggest they could offer therapeutic benefits in mood disorders, especially for patients with coexisting metabolic dysfunction or resistance to standard treatments [15,19,20]