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However, there are still major uncertainties regarding the reasons that limit the use of GLP-1 RAs, or what could be done to close the gap with guideline recommendations

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they are the baseline

In the UK, the Medicines and Healthcare products Regulatory Agency (MHRA) has issued warnings about severe dehydration in people taking these injections

The increased inflammatory response has a direct impact on gingival health meaning you are more likely to have problems with gingivitis and periodontitis. Gingivitis is inflammation of the gums, while periodontitis is a more advanced and destructive form of gum disease