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Results The prevalence proportion of GLP-1 RA dispensations in Region Stockholm increased from 4.7 patients/1000 inhabitants in 2019 to 17.5 patients/1000 inhabitants in 2023, and the incidence proportion from 1.8 patients/1000 inhabitants in 2019 to 7.4 patients/1000 inhabitants in 2023

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Astrazeneca AB has synthesized octahydrofuro[3,4-b]pyrazines acting as glucagon-like peptide 1 receptor (GLP-1R) agonists reported to be useful for the treatment of type 2 diabetes, cardiovascular and metabolic disorders.

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These label expansions unlocked new pathways for coverage, and by early 2025 the proportion of Medicare patients with diabetes or obesity initiating GLP-1 therapy rose sharply