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In a phase II trial, nondiabetic individuals with obesity shed 24.2% of their body weight on average after 48 weeks

When Providers Consider Modified Dosing Schedules Providers may discuss alternative dosing frequencies if a patient experiences significant gastrointestinal side effects at standard weekly doses, shows exceptional early response suggesting potential for optimization, or has metabolic markers suggesting altered GLP-1 pathway sensitivity

whereas, their role in T2D (Type 2 diabetes), historically considered to not be an immune-mediated condition, has not been clarified yet (5)

Adequate protein intake is particularly critical because rapid weight loss can lead to significant muscle loss alongside fat loss

Long-term support available: Ensure the telehealth service has long-term use plans available to maintain weight loss results