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There would be no grandfathering or exemptions for existing patients, she added

Post hoc evaluations of the SUSTAIN 6 trial revealed that semaglutide markedly increased the incidence of diabetic retinopathy complications in individuals with a history of retinopathy, especially among insulin users, presumably due to the swift deterioration of pre-existing retinopathy following rapid glycemic control [91]

[4] These gastrointestinal symptoms are often mild to moderate in severity and tend to diminish over time as the body adjusts to the medication

The definition of an ocular complication also varied in severity

Patients with a history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2) should avoid these medications due to the potential risk of thyroid C-cell tumors
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