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Daily oral semaglutide and once weekly injectable semaglutide have a generally similar efficacy and safety profile

Barmmer recommends that GLP-1 users planning to conceive undergo targeted nutrition therapy and consider tapering off the medication eight to ten weeks before attempting pregnancy

The endogenous GLP-1 hormone is rapidly degraded by the enzyme dipeptidyl peptidase-4 (DPP-4), resulting in a half-life of less than 5 min in the circulation (2, 3)

Symptoms and Warnings Signs to Look Out For If youre concerned that the use of GLP-1 medication has caused a serious health issue, here are the most common warning signs of the complications described above: Frequent nausea Excessive vomiting Acid reflux (GERD) Severe abdominal pain Bloating or swelling of the abdomen Loss of appetite Lack of bowel movements If you have experienced any of the listed symptoms, seek medical attention right away

One single case of exposure to liraglutide in the first trimester has been reported, describing a favourable outcome for the newborn