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People often do best when they focus on eating enough protein to help preserve muscle mass, building regular movement into their week, and gradually improving sleep and routines where possible

Biomed Res Int

Participants were randomised to liraglutide or placebo

Exendin-4 significantly increased insulin level and phosphorylation of insulin receptor substrate 1 (IRS-1) in rat hippocampus, and could not change the status of tau phosphorylation without insulin in HT22 neurons, suggesting that insulin is required in reduction of tau hyperphosphorylation by GLP-1R agonists (154)