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A large, retrospective study conducted by scientists at The University of Texas at San Antonio suggests that people taking glucagon-like peptide-1 (GLP-1) receptor agonists medications that are widely prescribed for metabolic disease have a significantly lower risk of developing colorectal cancer compared with those taking aspirin.

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A number of investigational new drugs targeting GLP-1R, GIPR and GDF-8 pathways are under clinical trials (Table 2)

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