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Recent studies reported that GLP-1R agonists, such as Val 8 -GLP-1(7-36), exendin-4 and liraglutide, attenuated A 1-42 -induced calcium overload by regulating intracellular calcium homeostasis in cortical or hippocampal pyramidal cells (173, 205, 206)

The mechanisms and cell types important for DPP-4mediated control of glucose and islet function have been extensively studied in humans and mice

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