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Liraglutide has been approved for multiple indications since its initial launch in 2010: 2010: Victoza approved for adults with type 2 diabetes 2014: Brand name Saxenda approved for obesity in adults 2017: Victoza approved for reducing the risk of major adverse cardiovascular (CV) events, heart attack, stroke, and CV death in adults with type 2 diabetes and established CV disease 2019: Victoza approved for pediatric patients aged ten and over with type 2 diabetes 2020: Saxenda approved for obesity in adolescents aged 12-17 Population According to the CDC, approximately 38 million adults in the United States have diabetes (90-95% is type 2 diabetes)

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Additionally, GLP-1 receptor agonists reduce gastrointestinal motility more broadly, which may contribute to sensations of bloating, fullness, and the need to expel gas orally