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Description

They are observed for one year and are followed in a Phase 1 open-label extension (NCT05400330)

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Seek urgent medical assessment if you develop: Difficulty swallowing (dysphagia) at any age Persistent or recurrent vomiting Unexplained weight loss, particularly if you're 55 or older and also have upper abdominal pain, reflux or dyspepsia Signs of gastrointestinal bleeding (such as black, tarry stools or vomiting blood) Iron-deficiency anaemia A lump or mass in the upper abdomen These symptoms require prompt evaluation as they may indicate more serious conditions requiring investigation, in line with NICE guidance for suspected cancer referrals

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