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In the SURPASS-2 trial, tirzepatide at doses of 5, 10, and 15 mg/week were compared with 1 mg/week semaglutide, and the 5 mg/week tirzepatide dose was found to be only slightly more effective than semaglutide in reducing both HbA 1c (2.01% vs

Danuglipron demonstrated significant efficacy in weight reduction

There are no known treatments to reverse this type of vision loss. Experts arent yet sure why this happens but continue to study this closely

Pregnancy is another important contraindication weight-loss medications including GLP-1 RAs are not used in pregnancy (intentional weight loss is not recommended for pregnant women, and animal studies with GLP-1 RAs have shown some fetal growth effects)

The problem with that is that's a huge pain in the tuchus to apply