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This pattern reflects the drug's mechanism: semaglutide works by regulating appetite hormones and metabolic signals, so discontinuation removes that biological support unless lifestyle modifications have produced durable metabolic change

[DOI] [PubMed] [Google Scholar] 33.Lingvay I, Brown-Frandsen K, Colhoun HM, et al

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Type 1 diabetes explained Type 1 diabetes is a life-long condition in which your pancreas doesnt make a hormone called insulin