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Description
Started with the lowest dose in February
It enrolled 445 adults with obesity (or overweight with complications) and knee osteoarthritis
Implications for Development Phase 1 results informed dose selection for Phase 2 trials, identifying optimal dosing ranges that balanced efficacy with tolerability
This translated to a 1.6 point drop in BMI, compared to 1.1 for the placebo
In the SURMOUNT-1 trial, Mounjaro helped people lose up to 22.5% of their starting body weight at 72 weeks
