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However, its clinical benefits are limited by its short half-life, which is less than 2 min because of its small size and rapid enzymatic inactivation by dipeptidyl peptidase IV

Semaglutide dosing follows a structured escalation protocol, typically reaching 2.4 mg weekly at maintenance

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Start with low-dose metoclopramide (5-10 mg three times daily before meals) or prochlorperazine (5-10 mg four times daily) as first-line antiemetic therapy f...

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