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Gastroenterology 122:531544 Drucker DJ, Yusta B, Boushey RP et al (1999) Human [Gly2]GLP-2 reduces the severity of colonic injury in a murine model of experimental colitis
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Some sensitive patients may benefit from microdosing (below 0.25 mg) or customized compounded formulations to improve tolerance
However, severe constipation persisting beyond 3 weeks, abdominal pain, rectal bleeding, or signs of bowel obstruction require immediate medical attention
