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The Ozempic prescribing information includes a warning about acute kidney injury and worsening of existing kidney problems, and states that "a majority of the reported events occurred in patients who had experienced nausea, vomiting, diarrhea, or dehydration." The same label tells doctors to counsel patients "of the potential risk of dehydration due to gastrointestinal adverse reactions and take precautions to avoid fluid depletion." The Mounjaro label carries the same class warning and advises doctors to "monitor renal function in patients reporting adverse reactions to MOUNJARO that could lead to volume depletion." It helps to keep this in perspective

Jesse Plemons Jesse Plemons weight loss journey began roughly around the same time the Ozempic fad took over showbiz

Nothing dramatic happened

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In a December report on its website, the FDA said some compounders were using salt forms of semaglutide in their agents, which are different from the ingredients used in Novo Nordisks FDA-approved versions of the drug