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For example, a 72-week phase II trial involving 320 patients with MASH, reported MASH resolution rates of up to 59% at the highest dose of 0.4 mg daily as compared to 17% in the placebo group

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The metabolic protection of maintained muscle mass becomes the primary defense against the caloric surplus that drives weight regain

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Some patients report feeling queasy for a few hours after taking the medication, which can sometimes interfere with daily activities

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not all participants achieved significant weight loss

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