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Consequently, identifying the effects of new adipokines will help in the development of new therapeutic strategies for obesity-induced diseases

These glial cells release a variety of pro-inflammatory agents, such as chemokines and cytokines, in order to address the insult [97]

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Leptin agonism of the leptin receptor (LEPR) on CD8+ T cells suppresses CD8+ TIL effector function, while CD8+ T cells lacking LEPR limit tumor growth in Rag2 -/- mice to a greater extent than LEPR-expressing T cells 9,42

At the same time, new clinical findings show semaglutide may actually reduce alcohol cravings and drinking behavior in those with alcohol use disorder