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GLP-1 agonists were originally approved to treat Type 2 Diabetes (T2D) but their most recent incarnations, which consist of both next generation GLP-1s and combinations (Ozempic, Mounjaro, Wegovy, Zepbound), have moved beyond the realm of T2D into the treatment of obesity

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GLP-1 medications generally do not produce these psychological effects, though the rapid change in relationship with food can create its own psychological adjustment

and inter alia, further down-regulates insulin function and thereby exacerbates Metabolic Syndrome
