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Typical treatment duration Most tirzepatide treatment courses run 12 to 18 months for initial weight loss, followed by an indefinite maintenance period

It enhances insulin secretion while uniquely improving lipid (fat) metabolism and buffering the brain against nausea typically triggered by GLP-1 stimulation

10.3389/fcell.2022.950623 [DOI] [PMC free article] [PubMed] [Google Scholar] 92.Liu WJ, Jin HY, Lee KA, Xie SH, Baek HS, Park TS (2011) Neuroprotective effect of the glucagon-like peptide-1 receptor agonist, synthetic exendin-4, in streptozotocin-induced diabetic rats
