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How Weight Loss Reduces Psoriasis Flare-Ups and Inflammation Adipose tissue functions as an endocrine organ, actively secreting inflammatory mediators including TNF-alpha, IL-6, and IL-17the same cytokines that drive psoriatic immune dysfunction

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Side Effects: What to Expect from Each Medication Foundayo Side Effects Common (occurring most often during dose escalation): Nausea Constipation Diarrhea Vomiting Indigestion / abdominal pain Hair loss (noted more than with injectable GLP-1s) Discontinuation due to adverse events: 5.310.3% depending on dose, vs 2.7% placebo (ATTAIN-1)