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Schedule a non-urgent appointment if you experience new or worsening anxiety symptoms, recurrent episodes of intense fear or discomfort accompanied by physical symptoms (palpitations, sweating, trembling, shortness of breath), persistent nausea or vomiting that interferes with medication adherence or nutrition, or symptoms that consistently occur in temporal relationship to tirzepatide injections

I felt a bit of fatigue at this point but persisted with the same slightly increased dose for week 4

A mental health professional can play an important role in helping people commit to long-term changes

This represents an improvement over the ~15% weight loss seen over a similar time period in Wegovy clinical trials, though cross trial comparisons are unreliable