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it indicates that, as of the current authorised safety profile, there is insufficient evidence to include these outcomes as expected adverse drug reactions with estimable frequency
The Food and Drug Administration label for semaglutide the active ingredient in many weight loss drugs says it may increase the risk of bone fractures in older adults and women
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The NICE guidance on perioperative care (NG180) emphasises the importance of individualised care and shared decision-making throughout the perioperative period
