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Studies of both mice and humans show the anti-inflammatory effects (such as reductions in TNF-) occur within hours, suggesting some actions are independent of weight loss or long-term metabolic change

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GLP-1 Effects on the Liver As endogenous intestinal-secreted GLP-1 is absorbed into the liver through the portal vein, the liver is highly involved in GLP-1 regulation [73]

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Link Henshaw D, Sparler N, Talbott A, et al

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