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In South Africa, it is a Schedule 4 medicine authorised for type 2 diabetes in adults

Numerous studies, many of them in animals, have shown that the body seeks quick energy under stress, leading to increased food intake

The participants had a mean baseline eGFR of 43 ml/min per 1.73 m 2 , and the slope of eGFR decline from baseline to 30 months was 2.86 ml/min per 1.73 m 2 for dapagliflozin and 3.79 ml/min per 1.73 m 2 per year for placebo, resulting in a between-group difference of 0.93 ml/min per 1.73 m 2 per year (95% CI 0.611.25)