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Other clinically relevant GI complications include cholelithiasis, which occurred about 50 % more often, and gastroesophageal reflux disease (GERD), which occurred roughly twice as often, in patients receiving GLP-1 therapies compared with placebo [33]

In May 2024, as second study in the New England Journal of Medicine found that the risk of a primary heart or kidney event was 24% lower in the semaglutide group

[DOI] [PubMed] 13.Song GJ, et al

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Side effects can still happen, they may not work for everyone, and medication works best alongside healthy nutrition, movement, and ongoing medical guidance
