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Linaclotide Linaclotide, an orally administered guanylate cyclase-C (GC-C) agonist, and its active metabolite binds to GC-C receptors on intestinal enterocytes, resulting in an increase in the intracellular concentration of cyclic guanosine monophosphate (cGMP), which regulates secretion of intestinal fluid

doi: 10.1038/s41587-023-02060-8

Read MoreBrittany KellyLong Island NY Hands-On Online didactic material was comprehensive and thoroughly addressed all aspects of treatment

But they dont teach people how to respond to setbacks or maintain progress when life gets complicated

Most patients find that symptoms improve with time and appropriate self-management measures